Bioinformatics. 2003 May 1;19(7):889-90.

R/qtl: QTL mapping in experimental crosses.

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Department of Biostatistics, Johns Hopkins University, 615 N. Wolfe St, Baltimore, MD 21205, USA. kbroman@jhsph.edu

Abstract

SUMMARY: R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by multiple methods, with the possible inclusion of covariates. AVAILABILITY: The package is freely available at http://www.biostat.jhsph.edu/~kbroman/qtl.

PMID:: 12724300; [PubMed - indexed for MEDLINE]

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