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Br J Psychiatry. 2003 May;182:449-54.

Mild cognitive impairment: prevalence and incidence according to different diagnostic criteria. Results of the Leipzig Longitudinal Study of the Aged (LEILA75+).

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  • 1Department of Psychiatry, University of Leipzig, Germany. krausem@medizin.uni-leipzig.de

Abstract

BACKGROUND:

Although mild cognitive impairment is associated with an increased risk of developing dementia, there has been little work on its incidence and prevalence.

AIMS:

To report age-specific prevalence, incidence and predictive validities for four diagnostic concepts of mild cognitive impairment.

METHOD:

A community sample of 1045 dementia-free individuals aged 75 years and over was examined by neuropsychological testing in a three-wave longitudinal study.

RESULTS:

Prevalence rates ranged from 3% to 20%, depending on the concept applied. The annual incidence rates applying different case definitions varied from 8 to 77 per 1000 person-years. Rates of conversion to dementia over 2.6 years ranged from 23% to 47%.

CONCLUSIONS:

Mild cognitive impairment is frequent in older people. Prevalence, incidence and predictive validities are highly dependent on the diagnostic criteria applied.

PMID:
12724250
[PubMed - indexed for MEDLINE]
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