[Hormonal abnormalities in women with breast cysts]

Ginekol Pol. 2002 Nov;73(11):1117-25.
[Article in Polish]

Abstract

Objectives: Increased estrogen activity and prolactin hypersecretion is a hormonal reason for Benign Breast Diseases.

Design: To evaluate hormonal disorders in women with gross breast cysts.

Material and methods: 30 women with gross breast cysts (over 10 mm in diameter) have been investigated. Cytohormonal vaginal swabs and serum levels of prolactin, estradiol and gonadotropins were evaluated.

Results: Normal prolactin levels were found in 96.7% of cases, but in 8 women with recurrent breast cysts after repeated FNA-biopsies prolactin secretion stimulated by metoclopramide was significantly increased. Low progesterone activity in all women and low estrogen activity in 65.3% were shown. Absolute high estrogen activity was diagnosed only in 8.7% women with gross breast cysts.

Conclusions: Nearly all patients with gross breast cysts have normal prolactin and low progesterone levels. High estrogen levels appear very seldom and in most cases these patients are hypoestrogenic.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Biomarkers / blood
  • Estradiol / blood*
  • Female
  • Fibrocystic Breast Disease / blood*
  • Fibrocystic Breast Disease / physiopathology
  • Gonadotropins, Pituitary / blood*
  • Humans
  • Immunoenzyme Techniques
  • Middle Aged
  • Prolactin / blood*
  • Time Factors

Substances

  • Biomarkers
  • Gonadotropins, Pituitary
  • Estradiol
  • Prolactin