Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Trends Biochem Sci. 2003 Apr;28(4):182-8.

Regulation of mRNA translation by 5'- and 3'-UTR-binding factors.

Author information

  • 1MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK.


The translational regulation of specific mRNAs is important for controlling gene expression. The past few years have seen a rapid expansion in the identification and characterization of mRNA regulatory elements and their binding proteins. For the majority of these examples, the mechanism by which translational regulation is achieved is not well understood. Nevertheless, detailed analyses of a few examples show that almost every event in the initiation pathway, from binding of the cap complex to the joining of the 60S ribosomal subunit, is subject to regulation.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk