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Neurology. 2003 Apr 22;60(8):1374-7.

Mild cognitive impairment: Can FDG-PET predict who is to rapidly convert to Alzheimer's disease?

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  • 1INSERM EO 218, University of Caen, Cyceron PET Center, France.

Abstract

Patients with mild cognitive impairment (MCI) were assessed, and a metabolic profile associated with conversion to AD at 18-month follow-up was sought. As compared with nonconverters (n = 10), converters (n = 7) had lower fluorodeoxyglucose uptake in the right temporoparietal cortex (p = 0.02, corrected for cluster size), without individual overlap. Awaiting replication in an independent sample, these findings suggest that among patients with MCI, fluorodeoxyglucose PET may accurately identify rapid converters.

PMID:
12707450
[PubMed - indexed for MEDLINE]
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