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Genome Biol. 2003;4(4):R28. Epub 2003 Mar 25.

GoMiner: a resource for biological interpretation of genomic and proteomic data.

Author information

  • 1Genomics and Bioinformatics Group, Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

Abstract

We have developed GoMiner, a program package that organizes lists of 'interesting' genes (for example, under- and overexpressed genes from a microarray experiment) for biological interpretation in the context of the Gene Ontology. GoMiner provides quantitative and statistical output files and two useful visualizations. The first is a tree-like structure analogous to that in the AmiGO browser and the second is a compact, dynamically interactive 'directed acyclic graph'. Genes displayed in GoMiner are linked to major public bioinformatics resources.

PMID:
12702209
[PubMed - indexed for MEDLINE]
PMCID:
PMC154579
Free PMC Article
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