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Arch Pathol Lab Med. 2003 Apr;127(4):478-80.

Severe gastritis secondary to Epstein-Barr viral infection. Unusual presentation of infectious mononucleosis and associated diffuse lymphoid hyperplasia in gastric mucosa.

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  • 1Department of Pathology and Laboratory Medicine, University of Wisconsin Hospital and Clinics, Madison, Wis, USA.

Abstract

Infectious mononucleosis is usually a self-limited clinical syndrome caused by primary Epstein-Barr virus infection. It is occasionally compounded by severe complications involving many different organ systems. Predominant gastrointestinal involvement is rarely documented. We present an unusual case of acute Epstein-Barr virus infection-associated gastritis with diffuse atypical lymphoid hyperplasia in gastric mucosa. The clinical, radiographic, histopathologic, immunohistochemical, and in situ hybridization features needed for accurate diagnosis and differentiation from gastric malignancies are discussed.

PMID:
12683879
[PubMed - indexed for MEDLINE]
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