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Curr Opin Genet Dev. 2003 Apr;13(2):136-42.

Recent advances in understanding chromatin remodeling by Swi/Snf complexes.

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  • 1Department of Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA.

Abstract

Members of the Swi/Snf family of chromatin-remodeling complexes play critical roles in transcriptional control. Recent studies have made significant advances in our understanding of the fundamental aspects of Swi/Snf complexes, including the roles of specific subunits, the repression of transcription, and the mechanism of remodeling. In addition, new findings also indicate an important role for the Swi/Snf-related complex, RSC, in controlling gene expression.

PMID:
12672490
[PubMed - indexed for MEDLINE]
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