Macrocyclic inhibitors of the NS3 protease as pote...[Angew Chem Int Ed Engl. 2003]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 0

Click to change filter selection through MyNCBI.

1: Angew Chem Int Ed Engl. 2003 Mar 28;42(12):1356-60. Links

Macrocyclic inhibitors of the NS3 protease as potential therapeutic agents of hepatitis C virus infection.

Tsantrizos YS, Bolger G, Bonneau P, Cameron DR, Goudreau N, Kukolj G, LaPlante SR, Llinàs-Brunet M, Nar H, Lamarre D.

Department of Chemistry, Boehringer Ingelheim, Canada, Ltd., Research and Development, 2100 Cunard Street, Laval, PQ H7S 2G5, Canada. ytsantrizos@lav.boehringer-ingelheim.com

PMID: 12671967 [PubMed - indexed for MEDLINE]

Bismacrocyclic inhibitors of hepatitis C NS3/4a protease.
Angew Chem Int Ed Engl. 2008; 47(47):9104-7.

[Angew Chem Int Ed Engl. 2008]
Design and synthesis of depeptidized macrocyclic inhibitors of hepatitis C NS3-4A protease using structure-based drug design.
J Med Chem. 2005 Aug 11; 48(16):5088-91.

[J Med Chem. 2005]
Resistance profiling of hepatitis C virus protease inhibitors using full-length NS3.
Antivir Ther. 2007; 12(5):733-40.

[Antivir Ther. 2007]
ReviewControl of hepatitis C: a medicinal chemistry perspective.
J Med Chem. 2005 Jan 13; 48(1):1-20.

[J Med Chem. 2005]
ReviewThe therapeutic potential of NS3 protease inhibitors in HCV infection.
Expert Opin Investig Drugs. 2005 Sep; 14(9):1129-44.

[Expert Opin Investig Drugs. 2005]
» See reviews... | » See all...

Cited by 2 PubMed Central articles

Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro.
Lu L, Pilot-Matias TJ, Stewart KD, Randolph JT, Pithawalla R, He W, Huang PP, Klein LL, Mo H, Molla A. Antimicrob Agents Chemother. 2004 Jun; 48(6):2260-6.

[Antimicrob Agents Chemother. 2004]
Hepatitis C virus subgenomic replicons in the human embryonic kidney 293 cell line.
Ali S, Pellerin C, Lamarre D, Kukolj G. J Virol. 2004 Jan; 78(1):491-501.

[J Virol. 2004]

Recent Activity

Clear Turn Off Turn On

Macrocyclic inhibitors of the NS3 protease as potential therapeutic agents of hepatitis C ...Macrocyclic inhibitors of the NS3 protease as potential therapeutic agents of hepatitis C virus infection.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

Macrocyclic inhibitors of the NS3 protease as potential therapeutic agents of hepatitis C virus infection.

Related articles

Cited by 2 PubMed Central articles

Recent Activity