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Nat Rev Genet. 2003 Apr;4(4):275-84.

Phylogeny estimation: traditional and Bayesian approaches.

Author information

  • 1Department of Ecology and Evolutionary Biology, 75 North Eagleville Road, University of Connecticut, Storrs, Connecticut 06269-3043, USA. mholder@uconn.edu

Abstract

The construction of evolutionary trees is now a standard part of exploratory sequence analysis. Bayesian methods for estimating trees have recently been proposed as a faster method of incorporating the power of complex statistical models into the process. Researchers who rely on comparative analyses need to understand the theoretical and practical motivations that underlie these new techniques, and how they differ from previous methods. The ability of the new approaches to address previously intractable questions is making phylogenetic analysis an essential tool in an increasing number of areas of genetic research.

PMID:
12671658
[PubMed - indexed for MEDLINE]
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