Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Nat Rev Immunol. 2003 Apr;3(4):304-16.

Immune functions encoded by the natural killer gene complex.

Author information

  • 1Howard Hughes Medical Institute, Rheumatology Division, Department of Medicine, Barnes-Jewish Hospital and Washington University School of Medicine, Box 8045, 660 South Euclid Avenue, St Louis, Missouri 63110, USA. yokoyama@imgate.wustl.edu


There has been marked progress in our understanding of the role of natural killer (NK) cells in immune responses, mainly due to the identification of NK-cell receptors and their ligands. The genes encoding many NK-cell receptors are located in the NK-gene complex (NKC). Here, we review the properties of NKC-encoded receptors, and provide a genomic and conceptual framework for an insight into NK-cell function and biology.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk