Management of intracranial aneurysms: factors that influence clinical grade and surgical outcome

South Med J. 2003 Mar;96(3):259-63. doi: 10.1097/01.SMJ.0000051906.95830.1F.

Abstract

Background: We report the experience in managing intracranial aneurysms at our medical center.

Methods: We retrospectively analyzed 297 intracranial aneurysms managed during a 6-year period. Risk factors were analyzed with respect to their influence on outcome after surgery as measured by Glasgow Outcome Scale score.

Results: Fifty-eight patients had multiple aneurysms. Of all aneurysms, 83% were in the anterior circulation, 37% were unruptured, and 59% were larger than 10 mm in size. Good outcomewas achieved in 75% of patients, and another 16% had fair outcomes. The mortality rate was 4%, and significant morbidity occurred in 5% of patients. Significant indicators of poor outcome were worsened clinical grade, posterior aneurysm location, and large aneurysm size.

Conclusion: Hypertensive patients, older patients, and patients with posterior circulation aneurysms had poorer neurologic status, which significantly influenced outcome. Larger aneurysms and vertebrobasilar aneurysms were associated with poor outcomes.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Female
  • Glasgow Outcome Scale
  • Humans
  • Intracranial Aneurysm / epidemiology
  • Intracranial Aneurysm / mortality
  • Intracranial Aneurysm / pathology
  • Intracranial Aneurysm / surgery*
  • Louisiana / epidemiology
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome