Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Science. 1976 May 21;192(4241):799-801.

Inherited retinal dystrophy: primary defect in pigment epithelium determined with experimental rat chimeras.

Abstract

Chimeric rats were produced by the aggregation of embryos of the pinkeyed, retinal dystrophic RCS strain with those of pigmented, normal rats. In the mosaic eyes, patches of neural retina with abnormal and degenerated photoreceptors were present only opposite patches of nonpigmented, mutant pigment epithelium. This indicates that the retinal dystrophy gene acts in the pigment epithelial cell rather than in the photoreceptor cell.

PMID:
1265483
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk