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Res Nurs Health. 2003 Apr;26(2):102-17.

Effects of stress management on PNI-based outcomes in persons with HIV disease.

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  • 1School of Nursing, Virginia Commonwealth University School of Nursing, Richmond, VA 23298-0567, USA.


A pretest-posttest, repeated-measures design was used to evaluate the effects of two stress management interventions on a battery of outcomes derived from a psychoneuroimmunological (PNI) framework. The effects of cognitive-behavioral relaxation training groups (CBSM) and social support groups (SSG) were compared with a WAIT-listed control group on the outcomes of psychosocial functioning, quality of life, neuroendocrine mediation, and somatic health. Participants were 148 individuals (119 men, 29 women), diagnosed with HIV disease; 112 (76%) completing the study groups. Using analysis of covariance, the CBSM group was found to have significantly higher postintervention emotional well-being and total quality-of-life scores than did either the SSG or WAIT groups. SSG participants had significantly lower social/family well-being scores immediately postintervention and lower social support scores after 6 months. The findings point to a pressing need for further, well-controlled research with these common intervention modalities.

Copyright 2003 Wiley Periodicals, Inc. Res Nurs Health 26:102-117, 2003

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