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    Bioinformatics. 2003 Mar 22;19(5):655-6.

    Gene expression data preprocessing.

    Source

    Unidad de Bioinformática, Centro Nacional de Investigaciones Oncológicas (CNIO), Melchor Fernández Almagro, 3 28029 Madrid, Spain.

    Abstract

    We present an interactive web tool for preprocessing microarray gene expression data. It analyses the data, suggests the most appropriate transformations and proceeds with them after user agreement. The normal preprocessing steps include scale transformations, management of missing values, replicate handling, flat pattern filtering and pattern standardization and they are required before performing any pattern analysis. The processed data set can be sent to other pattern analysis tools.

    PMID:
    12651726
    [PubMed - indexed for MEDLINE]
    Free full text

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