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Biochim Biophys Acta. 2003 Mar 10;1610(2):187-97.

Phospholipid/cholesterol model membranes: formation of cholesterol crystallites.

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  • 1Department of Biological Chemistry, Weizmann Institute of Science, Rehovot, 76100, Israel.


Experimental data that define conditions under which cholesterol crystallites form in cholesterol/phospholipid model membranes are reviewed. Structural features of the phospholipids that determine cholesterol crystallization include the length and degree of unsaturation of the acyl chains, the presence of charge on the headgroups and interheadgroup hydrogen bonds.

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