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Curr Diab Rep. 2003 Feb;3(1):56-9.

Mastopathy and diabetes.

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  • 1Division of Endocrinology and Metabolism, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA.


Sclerosing lymphocytic lobulitis or "diabetic mastopathy" is strongly associated with type 1 diabetes but may occur occasionally in its absence. It is characterized by keloid-type fibrosis, lymphocytic lobulitis, and perivasculitis and epithelioid cells. Infiltrating cells are predominantly B lymphocytes. It may be associated with retinopathy and neuropathy, but more research is needed to verify this association. The etiopathogenesis is unknown and the disorder does not seem to predispose to breast carcinoma or lymphoma.

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