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Gastroenterol Clin North Am. 2003 Mar;32(1):323-40.

Inflammatory bowel disease in pregnancy.

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  • Division of Gastroenterology, Department of Medicine, University of Chicago, 5841 South Maryland Avenue, MC 4076, Chicago, IL 60637, USA. skane@medicine.bsd.uchicago.edu


Fertility is affected in ulcerative colitis after surgery and in active Crohn's disease. Adverse fetal outcomes are not increased when IBD is quiescent. Active disease at conception increases the risk of adverse fetal outcomes. Most medications for IBD are safe during pregnancy and breastfeeding, with notable exceptions. Active disease is usually more deleterious than maintaining medical therapy.

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