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Arch Neurol. 2003 Mar;60(3):437-40.

Right orbitofrontal tumor with pedophilia symptom and constructional apraxia sign.

Author information

  • 1Department of Neurology, University of Virginia Health System, 1 Hospital Dr, Charlottesville, VA 22908, USA.

Abstract

BACKGROUND:

Orbitofrontal abnormalities are associated with poor impulse control, altered sexual behavior, and sociopathy.

OBJECTIVE:

To describe a patient with acquired pedophilia and a right orbitofrontal tumor who was unable to inhibit sexual urges despite preserved moral knowledge.

DESIGN:

Case report.

RESULTS:

The patient displayed impulsive sexual behavior with pedophilia, marked constructional apraxia, and agraphia. The behavioral symptoms and constructional deficits, including agraphia, resolved following tumor resection.

CONCLUSIONS:

For patients with acquired sociopathy and paraphilia, an orbitofrontal localization requires consideration. This case further illustrates that constructional apraxia can arise from right prefrontal lobe dysfunction. Agraphia may represent a manifestation of constructional apraxia in the absence of aphasia and ideomotor apraxia.

PMID:
12633158
[PubMed - indexed for MEDLINE]
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