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    Arch Neurol. 2003 Mar;60(3):437-40.

    Right orbitofrontal tumor with pedophilia symptom and constructional apraxia sign.

    Source

    Department of Neurology, University of Virginia Health System, 1 Hospital Dr, Charlottesville, VA 22908, USA.

    Abstract

    BACKGROUND:

    Orbitofrontal abnormalities are associated with poor impulse control, altered sexual behavior, and sociopathy.

    OBJECTIVE:

    To describe a patient with acquired pedophilia and a right orbitofrontal tumor who was unable to inhibit sexual urges despite preserved moral knowledge.

    DESIGN:

    Case report.

    RESULTS:

    The patient displayed impulsive sexual behavior with pedophilia, marked constructional apraxia, and agraphia. The behavioral symptoms and constructional deficits, including agraphia, resolved following tumor resection.

    CONCLUSIONS:

    For patients with acquired sociopathy and paraphilia, an orbitofrontal localization requires consideration. This case further illustrates that constructional apraxia can arise from right prefrontal lobe dysfunction. Agraphia may represent a manifestation of constructional apraxia in the absence of aphasia and ideomotor apraxia.

    PMID:
    12633158
    [PubMed - indexed for MEDLINE]

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