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    J Nerv Ment Dis. 1976 May;162(5):366-71.

    Treatment of chronic post-traumatic organic brain syndrome with dextroamphetamine: first reported case.

    Abstract

    In view of its therapeutic efficacy in the treatment of children with minimal brain dysfunction syndrome, dextroamphetamine was administered to a young adult with a chronic organic brain syndrome secondary to cerebral trauma. That D-amphetamine was critical to the resulting marked diminution in confusion, paranoia, and deficit in short term memory was confirmed by the occurrence of a relapse coincident with placebo administration as part of a double blind evaluation. Amitriptylline appeared to potentiate the therapeutic effects of D-amphetamine. The results achieved, although observational and subjective in nature, warrant replication in controlled, quantitative clinical studies.

    PMID:
    1262859
    [PubMed - indexed for MEDLINE]

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