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Clin Infect Dis. 2003 Mar 15;36(6):786-8. Epub 2003 Mar 3.

Smallpox vaccination and the patient with an organ transplant.

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  • 1Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. lesia@jhmi.edu


Organ transplant recipients are vulnerable to a variety of infections because of the immunosuppressed state required to prevent organ rejection. We review the recommendations of the Centers for Disease Control and Prevention (Atlanta, Georgia) for smallpox vaccination and the possible complications of vaccination in the population with organ transplants. The risk of these complications is presumably dependent on the extent of deficient cell-mediated immunity.

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