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1: Physiol Res. 2003;52(1):137-40.Click here to read Links

Heart rate and increased intravascular volume.

First Internal Cardio-Angiology Clinics, St. Anna Teaching Hospital, Brno, Czech Republic. miroslav.soucek@fnusa.cz

The objective was to establish whether an intravascular volume increase leads to a heart rate (HR) increase without increased sympathetic tonus. HR changes at rest and at deep breathing (6/min - simulated increase of atrial filling pressure) were measured in patients after heart transplantation. Evaluation of dependency of HR changes on breathing depth was done through a new time series methodology. The data was evaluated through graphs displaying a significant increase in the graph area at deep breathing, when compared with breathing at rest (p<0.01). We presume that an increase in HR corresponds to increased intravascular volume and malfunctioning kidneys.

PMID: 12625819 [PubMed - indexed for MEDLINE]