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Mol Cell. 2003 Feb;11(2):289-91.

Enforced proximity in the function of a famous scaffold.

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  • 1Department of Molecular Pharmacology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Abstract

Recent studies by Park, Zarrinipar, and Lim with reengineered Ste5 scaffold proteins underscore the fundamental importance of proximity in enzyme regulation and of keeping a proper distance for maintaining signaling specificity.

PMID:
12620218
[PubMed - indexed for MEDLINE]
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