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Curr Biol. 2003 Mar 4;13(5):R195-7.

Transcriptional activation: getting a grip on condensed chromatin.

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  • Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Biotech 2, Suite 210, Worcester, MA 01605, USA. craig.Peterson@umassmed.edu


Chromosomal transcription involves the concerted action of enormous, multisubunit chromatin remodeling complexes. A recent study, however, suggests a different and surprising viewpoint in which these protein assemblies are quite dynamic and individual subunits play key roles in chromatin remodeling.

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