Excision and integration of cassettes by an integron integrase of Nitrosomonas europaea

J Bacteriol. 2003 Mar;185(6):2036-41. doi: 10.1128/JB.185.6.2036-2041.2003.

Abstract

We found in the environmental strain Nitrosomonas europaea a chromosomal integron-like structure with an integrase gene, intI(Neu). We have tested the capacity of the IntINeu integrase to excise and integrate several resistance gene cassettes. The results allow us to consider IntINeu a new functional integron integrase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Attachment Sites, Microbiological
  • Base Sequence
  • Drug Resistance, Bacterial / genetics
  • Integrases / genetics
  • Integrases / metabolism*
  • Molecular Sequence Data
  • Nitrosomonas / drug effects
  • Nitrosomonas / enzymology*
  • Nitrosomonas / genetics
  • Phylogeny
  • Plasmids
  • Polymerase Chain Reaction
  • Recombination, Genetic*
  • Sequence Alignment

Substances

  • Integrases
  • integron integrase IntI1