Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):554-66. Epub 2003 Feb 6.

Noninvasive assessment of arterial stiffness and risk of atherosclerotic events.

Source

Clinical Pharmacology Unit and Research Centre, University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, Scotland, UK. James.Oliver@ed.ac.uk

Abstract

Investigation of arterial stiffness, especially of the large arteries, has gathered pace in recent years with the development of readily available noninvasive assessment techniques. These include the measurement of pulse wave velocity, the use of ultrasound to relate the change in diameter or area of an artery to distending pressure, and analysis of arterial waveforms obtained by applanation tonometry. Here, we describe each of these techniques and their limitations and discuss how the measured parameters relate to established cardiovascular risk factors and clinical outcome. We also consider which techniques might be most appropriate for wider clinical application. Finally, the effects of current and future cardiovascular drugs on arterial stiffness are also discussed, as is the relationship between arterial elasticity and endothelial function.

PMID:: 12615661; [PubMed - indexed for MEDLINE]

Free full text

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

ClinicalTrials.gov

Supplemental Content

Save items

Related citations in PubMed

Review Assessment of arterial stiffness, a translational medicine biomarker system for evaluation of vascular risk. [Cardiovasc Ther. 2008]
Review Assessment of arterial stiffness, a translational medicine biomarker system for evaluation of vascular risk.
Wang X, Keith JC Jr, Struthers AD, Feuerstein GZ. Cardiovasc Ther. 2008 Fall; 26(3):214-23.
Non-invasive assessment of arterial stiffness by pulse-wave velocity correlates with endothelial dysfunction. [Indian Heart J. 2005]
Non-invasive assessment of arterial stiffness by pulse-wave velocity correlates with endothelial dysfunction.
Jadhav UM, Kadam NN. Indian Heart J. 2005 May-Jun; 57(3):226-32.
Hypertension and arterial stiffness: the Atherosclerosis Risk in Communities Study. ARIC Investigators. [Am J Hypertens. 2000]
Hypertension and arterial stiffness: the Atherosclerosis Risk in Communities Study. ARIC Investigators.
Arnett DK, Boland LL, Evans GW, Riley W, Barnes R, Tyroler HA, Heiss G. Am J Hypertens. 2000 Apr; 13(4 Pt 1):317-23.
Review Arterial stiffness, hypertension, and rational use of nebivolol. [Vasc Health Risk Manag. 2009]
Review Arterial stiffness, hypertension, and rational use of nebivolol.
Agabiti-Rosei E, Porteri E, Rizzoni D. Vasc Health Risk Manag. 2009; 5(1):353-60.
Review Large-artery stiffness, hypertension and cardiovascular risk in older patients. [Nat Clin Pract Cardiovasc Med....]
Review Large-artery stiffness, hypertension and cardiovascular risk in older patients.
Blacher J, Safar ME. Nat Clin Pract Cardiovasc Med. 2005 Sep; 2(9):450-5.

See reviews... See all...

Cited by 38 PubMed Central articles

A prospective randomized controlled trial of the effects of vitamin d supplementation on cardiovascular disease risk. [PLoS One. 2012]
A prospective randomized controlled trial of the effects of vitamin d supplementation on cardiovascular disease risk.
Gepner AD, Ramamurthy R, Krueger DC, Korcarz CE, Binkley N, Stein JH. PLoS One. 2012; 7(5):e36617. Epub 2012 May 7.
Review Cardiovascular disease in systemic sclerosis--an emerging association? [Arthritis Res Ther. 2011]
Review Cardiovascular disease in systemic sclerosis--an emerging association?
Ngian GS, Sahhar J, Wicks IP, Van Doornum S. Arthritis Res Ther. 2011 Aug 26; 13(4):237. Epub 2011 Aug 26.
Relationship between vascular stiffness and stress myocardial perfusion imaging in asymptomatic patients with diabetes. [Eur J Nucl Med Mol Imaging. 2011]
Relationship between vascular stiffness and stress myocardial perfusion imaging in asymptomatic patients with diabetes.
Roos CJ, Djaberi R, Schuijf JD, de Koning EJ, Rabelink TJ, Smit JW, Pereira AM, Al Younis I, van der Hiel B, Scholte AJ, et al. Eur J Nucl Med Mol Imaging. 2011 Nov; 38(11):2050-7. Epub 2011 Aug 18.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Noninvasive assessment of arterial stiffness and risk of atherosclerotic events.
Noninvasive assessment of arterial stiffness and risk of atherosclerotic events.
Arterioscler Thromb Vasc Biol. 2003 Apr 1 ;23(4):554-66. Epub 2003 Feb 6 .

PubMed
Studies of malformation syndromes of man XXXXI B: nosologic studies in the Hanha...
Studies of malformation syndromes of man XXXXI B: nosologic studies in the Hanhart and the Möbius syndrome.
Eur J Pediatr. 1976 Apr 6 ;122(1):19-55.

PubMed
Heterocyclic amines, meat intake, and association with colon cancer in a populat...
Heterocyclic amines, meat intake, and association with colon cancer in a population-based study.
Am J Epidemiol. 2003 Mar 1 ;157(5):434-45.

PubMed
Immune responses of elk to Mycobacterium bovis bacillus Calmette Guerin vaccinat...
Immune responses of elk to Mycobacterium bovis bacillus Calmette Guerin vaccination.
Vaccine. 2003 Mar 28 ;21(13-14):1518-26.

PubMed
Differential and bi-directional regulation between TR2/TR4 orphan nuclear recept...
Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes.
J Dermatol Sci. 2003 Feb ;31(1):65-71.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Noninvasive assessment of arterial stiffness and risk of atherosclerotic events.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Cited by 38 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information