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Am J Psychiatry. 2003 Mar;160(3):566-8.

Parahippocampal gray matter density in panic disorder: a voxel-based morphometric study.

Author information

  • 1Institut Clínic de Psiquiatria i Psicologia, Corporació Sanitària Clínic, I.D.I.B.A.S., Barcelona, Catalonia, Spain. trocosmos@yahoo.es

Abstract

OBJECTIVE:

The authors examined possible cerebral gray matter abnormalities in patients with panic disorder.

METHOD:

Gray matter concentration in 18 panic disorder outpatients and 18 healthy subjects was compared by using a voxel-based morphometry approach.

RESULTS:

Gray matter density of the left parahippocampal gyrus was significantly lower in patients with panic disorder compared with healthy subjects.

CONCLUSIONS:

This result provides further support for the involvement of the parahippocampal area in the pathophysiology of panic disorder.

PMID:
12611840
[PubMed - indexed for MEDLINE]
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