Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Microb Cell Fact. 2003 Jan 30;2(1):1.

The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi.

Author information

  • 1TNO Nutrition and Food Research, Department of Applied Microbiology and Gene Technology, P,O, Box 360, 3700 AJ Zeist, The Netherlands. joosten@voeding.tno.nl

Abstract

In this review we will focus on the current status and views concerning the production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi. We will focus on single-chain antibody fragment production (scFv and VHH) by these lower eukaryotes and the possible applications of these proteins. Also the coupling of fragments to relevant enzymes or other components will be discussed. As an example of the fusion protein strategy, the 'magic bullet' approach for industrial applications, will be highlighted.

PMID:
12605725
[PubMed - as supplied by publisher]
PMCID:
PMC149433
Free PMC Article

Images from this publication.See all images (3)Free text

Figure 1
Figure 2
Figure 3
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Write to the Help Desk