Obsessive compulsive behaviour in autism--towards an autistic-obsessive compulsive syndrome?

World J Biol Psychiatry. 2001 Oct;2(4):193-7. doi: 10.3109/15622970109026809.

Abstract

A portion of autistic patients exhibit compulsive-like behaviours. In addition it has been suggested that serotonin plays a major role in both obsessive compulsive disorder (OCD) and autistic disorder. Other neurohumors such as endogenous opioids and oxytocin have also been implicated in the two disorders. There is also some pharmacological overlap between the two disorders, as well as some similar neuroimaging studies. These similarities and overlaps have led us to propose a putative OCD-autistic disorder, which should be studied in greater detail.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Autistic Disorder / complications*
  • Autistic Disorder / metabolism
  • Autistic Disorder / pathology
  • Brain / metabolism
  • Brain / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Obsessive-Compulsive Disorder / complications*
  • Obsessive-Compulsive Disorder / metabolism
  • Obsessive-Compulsive Disorder / pathology
  • Serotonin / metabolism
  • Terminology as Topic*

Substances

  • Serotonin