Crystal engineering of the composition of pharmaceutical phases

R D Bailey Walsh; M W Bradner; a S Fleischman; L A Morales; a B Moulton; N Rodríguez-Hornedo; M J Zaworotko

doi:10.1039/b208574g

Crystal engineering of the composition of pharmaceutical phases

Chem Commun (Camb). 2003 Jan 21:(2):186-7. doi: 10.1039/b208574g.

Authors

R D Bailey Walsh¹, M W Bradner, a S Fleischman, L A Morales, a B Moulton, N Rodríguez-Hornedo, M J Zaworotko

Affiliation

¹ Department of Chemistry, University of South Florida, 4202 E Fowler Ave (SCA 400), Tampa, FL 33620-5250, USA.

PMID: 12585383
DOI: 10.1039/b208574g

Abstract

The carboxylic acid-pyridine supramolecular heterosynthon can be exploited to predictably generate binary crystalline phases involving rac-ibuprofen, rac-flurbiprofen or aspirin.