Theor Appl Genet. 2002 Aug;105(2-3):423-430. Epub 2002 Jun 19.

Structure and expression of the Zea mays mutS-homologs Mus1 and Mus2.

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Institute of Genetics, University of Munich, Maria-Ward-Strasse 1a, 80638 München, Germany.

Abstract

DNA mismatch repair proteins play an important role in maintaining the integrity of the genetic information during replication and homologous recombination. The MutS-homologous (MSH) and MutL-homologous (MLH) proteins are highly conserved among all prokaryotes and eukaryotes. We have isolated two mutS homologous genes from Zea mays, named Mus1 and Mus2. Phylogenetic analysis identifies Mus1 as a member of the MSH2 protein family. Mus2 is an ortholog of the Arabidopsis thaliana MSH7 protein and belongs to a subgroup of MSH proteins that is possibly plant-specific. Mus1 and Mus2 are expressed at very low levels. Mus1 is located on chromosome 7L near locus b32B, and mus2 maps on chromosome 3S.

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Structure and expression of the Zea mays mutS-homologs Mus1 and Mus2.

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