Cell. 2003 Feb 7;112(3):284-6.

Circadian clocks: a tale of two feedback loops.

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Department of Neurobiology and Physiology, Northwestern University, Evanston, IL 60208, USA.

Abstract

Circadian clocks in a wide range of organisms are thought to consist of two interdependent transcriptional feedback loops. In Drosophila, the first loop has been well characterized and controls rhythmic period expression. In this issue of Cell, define a role for a transcriptional activator and a repressor in the second feedback loop.

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Cell. 2003 Feb 7;112(3):329-41.

PMID:: 12581517; [PubMed - indexed for MEDLINE]

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