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    Epilepsia. 2003 Jan;44(1):127-30.

    Bilateral Rasmussen encephalitis: postmortem documentation in a five-year-old.

    Tobias SM, Robitaille Y, Hickey WF, Rhodes CH, Nordgren R, Andermann F.

    Source

    Pathology Department, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756-0001, USA.

    Abstract

    A case of Rasmussen encephalitis with bilateral involvement and onset at age 2 years is reviewed. Rasmussen encephalitis is a rare progressive disease that causes intractable seizures, cognitive decline, and inflammatory changes in the brain. The neurologic involvement is characteristically unilateral. Bilateral involvement in this case was suspected within 5 months of presentation and was confirmed by bilateral frontal lobe biopsies. The severity and progression of the disease in this case was remarkable and resulted in the patient's death by age 5 years, despite numerous attempted therapeutic interventions. Autopsy findings confirmed the diagnosis of Rasmussen encephalitis with bilateral involvement.

    PMID:
    12581240
    [PubMed - indexed for MEDLINE]

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