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Neurology. 2003 Feb 11;60(3):492-5.

Evidence of cardiac ischemia during seizures in drug refractory epilepsy patients.

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  • 1Department of Neurology, Aarhus University Hospital, Aarhus, Denmark.


The authors investigated whether patients with drug refractory epilepsy have cardiovascular abnormalities that might be related to a high frequency of sudden death. Twenty-three subjects underwent comprehensive cardiovascular evaluations before and during video-EEG monitoring. ST-segment depression occurred in 40% and was associated with a higher maximum heart rate during seizures. These data suggest that cardiac ischemia may occur in these patients.

[PubMed - indexed for MEDLINE]
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