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1: Neurology. 2003 Feb 11;60(3):492-5.Click here to read Links
Comment in:
Neurology. 2003 Feb 11;60(3):363-4.
Neurology. 2004 Apr 13;62(7):1238-9; author reply 1239.

Evidence of cardiac ischemia during seizures in drug refractory epilepsy patients.

Tigaran S, Mølgaard H, McClelland R, Dam M, Jaffe AS.

Department of Neurology, Aarhus University Hospital, Aarhus, Denmark. mona@akhphd.au.dk

The authors investigated whether patients with drug refractory epilepsy have cardiovascular abnormalities that might be related to a high frequency of sudden death. Twenty-three subjects underwent comprehensive cardiovascular evaluations before and during video-EEG monitoring. ST-segment depression occurred in 40% and was associated with a higher maximum heart rate during seizures. These data suggest that cardiac ischemia may occur in these patients.

PMID: 12578934 [PubMed - indexed for MEDLINE]