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1: Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2000 Dec;14(12):573-5.Links

[Comparison of the effectiveness of levofloxacin and cefuroxime for the treatment of sinusitis]

[Article in Chinese]

Li XP, Qin ZM, Zheng RH, Tan QL, Zhou YY, Zhu L, Yin AF.

Department of Otolaryngology, Third Hospital, Beijing University, Beijing 100083.

OBJECTIVE: To observe the effectiveness of levofloxacin and cefuroxime for the treatment of sinusitis in adults. METHOD: Patients with acute or chronic sinusitis were randomly assigned to receive either levofloxacin (200 mg orally once daily, 200/100 mg twice daily) or cefuroxime (250 mg orally twice daily) for 10 to 14 days. Pre- or post-treatment, the clinical and laboratory examination were done and in the end of treatment, the efficacy and safety were assessment. RESULT: The success rates after the end of treatment were 97.4% for the 76 patients who received levofloxacin and 92.8% for the 14 patients who received cefuroxime. The resolution rates of bacteria were 91.6% and 80.0%, respectively. The safety of these two groups were more high. CONCLUSION: Levofloxacin is effective for the treatment of sinusitis in adults and pay attention to the course of treatment for raising the efficacy of treatment.

PMID: 12563960 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Levofloxacin (Levaquin® )

    Levofloxacin is used to treat certain infections such as pneumonia chronic bronchitis and sinus, urinary tract, kidney, prostate (a male reproductive gland), and skin infections. Levofloxacin is also used to prevent anth...

  • Ofloxacin (Floxin® )

    Ofloxacin is used to treat certain infections including bronchitis, pneumonia, and infections of the skin, bladder, urinary tract, reproductive organs, and prostate (a male reproductive gland). Ofloxacin is in a class of...

  • Cefuroxime (Ceftin® , Zinacef® )

    Cefuroxime is used to treat certain infections caused by bacteria, such as bronchitis; gonorrhea; Lyme disease; and infections of the ears, throat, sinuses, urinary tract, and skin. Cefuroxime is in a class of medication...

  • Source: AHFS Consumer Medication Information