Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Arch Pathol Lab Med. 2003 Jan;127(1):e22-4.

Carcinoid tumors of the urinary bladder. Immunohistochemical study of 2 cases and review of the literature.

Author information

  • 1Dipartimento di Patologia-Sezione Anatomia Patologica, Universita' di Verona, Verona, Italy.

Abstract

We report the clinical, histopathologic, and immunophenotypic features of 2 carcinoid tumors of the urinary bladder and review the literature. Both tumors were located in the bladder neck, presented with hematuria, were small, and appeared to be completely excised cystoscopically. The tumors were smooth-surfaced sessile polypoid nodules covered by urothelium. Both tumors had glandular architecture. One tumor had regular bland nuclei, and the other had focal moderate nuclear pleomorphism. Neuroendocrine differentiation was readily confirmed by the immunohistochemical markers chromogranin, synaptophysin, and neural cell adhesion molecule (CD56/NCAM). In 1 of the tumors, 20% of the cells were positive for the beta subunit of human chorionic gonadotropin, and 20% were positive for thyroid transcription factor 1.

PMID:
12562289
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Allen Press, Inc.
    Loading ...
    Write to the Help Desk