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Can Vet J. 2002 Dec;43(12):971-2.

Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler.

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  • 1Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.

Abstract

A mature male rottweiler was evaluated for acute collapse and abdominal pain. The history consisted of concurrent administration of meloxicam and aspirin. On exploratory laparotomy, a large perforated ulcer was discovered in the proximal duodenum, with secondary peritonitis. The pathogenesis of NSAID-induced gastrointestinal ulceration and the supposed safety of COX-2 selective agents are discussed.

PMID:
12561693
[PubMed - indexed for MEDLINE]
PMCID:
PMC339922
Free PMC Article
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