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Am J Med Sci. 2003 Jan;325(1):38-40.

Spontaneous tumor lysis syndrome in solid tumors: really a rare condition?

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  • 1Department of Medicine 'A', Western Galilee Hospital, Naharya, Israel.


Acute tumor lysis syndrome (ATLS), which occurs spontaneously, without cytotoxic therapy, is a rare condition. Spontaneous TLS (STLS) has been seen most commonly in lymphoma and leukemia. We report a series of 3 cases of STLS in patients with solid tumors who were hospitalized in our department during a 9-month period and suggest that STLS is probably more frequent than previously thought.

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