Your browser version may not work well with NCBI's Web applications. More information here...
1: J Dermatol. 2002 Dec;29(12):776-80.Click here to read Links

Antiphospholipid antibody syndrome complicated by Grave's disease.

Takahashi A, Tamura A, Ishikawa O.

Department of Dermatology, Gunma University School of Medicine, Maebashi, Gunma, Japan.

The report describes a woman with primary antiphospholipid antibody syndrome complicated with Grave's disease. Developing symptoms included a small cutaneous nodule on her finger and subsequently ecchymotic purpura on the cheeks, ears, buttocks and lower legs. Histological examinations showed thrombosed vessels in the dermis without or with hemorrhage, respectively. Laboratory investigation revealed positive lupus anticoagulant and immunogenic hyperthyroidism due to Grave's disease. There is a close relationship between the cutaneous manifestation of antiphospholipid antibody syndrome and the activities of Grave's disease and a possible link of antiphospholipid antibody syndrome with Grave's disease was suggested both by the etiology of the disease as well as the disease activity.

PMID: 12532043 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Thyroid (Armour® Thyroid)

    Thyroid is a hormone produced by the body. When taken correctly, thyroid is used to treat the symptoms of hypothyroidism (a condition where the thyroid gland does not produce enough thyroid hormone). Symptoms of hypothyr...

  • Source: AHFS Consumer Medication Information