Send to:

Choose Destination
See comment in PubMed Commons below
Neurocase. 2002;8(6):405-10.

Mild cognitive impairment: a clinically useful but currently ill-defined concept?

Author information

  • 1University Neurology Unit, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK.


The term mild cognitive impairment (MCI) has gained wide currency among clinicians, and particularly dementia researchers, to denote patients with memory deficits who do not yet fulfil the criteria for dementia, but are at high risk of conversion. MCI is therefore regarded as the prodromic or pre-dementia stage of Alzheimer's disease. The accurate categorization of these subjects has far-reaching implications, both for research in this field and for those individuals who fall within this diagnostic group. Despite a wealth of studies examining the neuropsychological, neuroimaging and biological profiles of this population, the characterization of MCI remains controversial. This brief overview discusses a number of the issues related to this topic and questions the currently accepted criteria.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk