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Heart. 2003 Feb;89(2):E7.

Protein C deficiency manifesting as an acute myocardial infarction and ischaemic stroke.

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  • 1Department of Internal Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

Abstract

Protein C deficiency is a disorder in the coagulation cascade that results in predominantly venous thromboembolism. However, recent studies have implicated this disorder as a possible contributor to arterial thrombosis, especially myocardial infarction. There are six reported cases of myocardial infarction secondary to protein C deficiency in the literature. This is the first report of myocardial infarction and ischaemic stroke in the same patient as a manifestation of protein C deficiency. The investigation of hypercoagulable state is an essential component of the investigation of young patients with myocardial infarction.

PMID:
12527693
PMCID:
PMC1767549
[PubMed - indexed for MEDLINE]
Free PMC Article
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