J Obstet Gynaecol. 2002 May;22(3):260-6.

Prenatal anger effects on the fetus and neonate.

Field T, Diego M, Hernandez-Reif M, Salman F, Schanberg S, Kuhn C, Yando R, Bendell D.

Source

Touch Research Institutes, Department of Pediatrics (D-820), University of Miami School of Medicine, PO Box 016820, Miami, FL 33101, USA. tfield@med.miami.edu

Abstract

One hundred and sixty-six women were classified as experiencing high or low anger during the second trimester of pregnancy. The high-anger women also had high scores on depression and anxiety scales. In a follow-up across pregnancy, the fetuses of the high-anger women were noted to be more active and to experience growth delays. The high-anger mothers' high prenatal cortisol and adrenaline and low dopamine and serotonin levels were mimicked by their neonates' high cortisol and low dopamine levels. The high-anger mothers and infants were also similar on their relative right frontal EEG activation and their low vagal tone. Finally, the newborns of high-anger mothers had disorganised sleep patterns (greater indeterminate sleep and more state changes) and less optimal performance on the Brazelton Neonatal Behavior Assessment Scale (orientation, motor maturity and depression). These data highlight the need for prenatal intervention for elevated angry mood during pregnancy.

PMID:: 12521495; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Grant Support

Publication Types

MeSH Terms

Grant Support

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Supplemental Content

Related citations

Pregnancy anxiety and comorbid depression and anger: effects on the fetus and neonate. [Depress Anxiety. 2003]
Pregnancy anxiety and comorbid depression and anger: effects on the fetus and neonate.
Field T, Diego M, Hernandez-Reif M, Schanberg S, Kuhn C, Yando R, Bendell D. Depress Anxiety. 2003; 17(3):140-51.
Relative right versus left frontal EEG in neonates. [Dev Psychobiol. 2002]
Relative right versus left frontal EEG in neonates.
Field T, Diego M, Hernandez-Reif M, Schanberg S, Kuhn C. Dev Psychobiol. 2002 Sep; 41(2):147-55.
Right frontal EEG and pregnancy/neonatal outcomes. [Psychiatry. 2002]
Right frontal EEG and pregnancy/neonatal outcomes.
Field T, Diego M, Hernandez-Reif M, Schanberg S, Kuhn C. Psychiatry. 2002 Spring; 65(1):35-47.
Review Prenatal depression effects on the fetus and newborn: a review. [Infant Behav Dev. 2006]
Review Prenatal depression effects on the fetus and newborn: a review.
Field T, Diego M, Hernandez-Reif M. Infant Behav Dev. 2006 Jul; 29(3):445-55. Epub 2006 May 30.
Review Prenatal depression effects on early development: a review. [Infant Behav Dev. 2011]
Review Prenatal depression effects on early development: a review.
Field T. Infant Behav Dev. 2011 Feb; 34(1):1-14.

See reviews... See all...

Cited by 4 PubMed Central articles

Stress during pregnancy and offspring pediatric disease: A National Cohort Study. [Environ Health Perspect. 2011]
Stress during pregnancy and offspring pediatric disease: A National Cohort Study.
Tegethoff M, Greene N, Olsen J, Schaffner E, Meinlschmidt G. Environ Health Perspect. 2011 Nov; 119(11):1647-52. Epub 2011 Jul 18.
Maternal depression and neurobehavior in newborns prenatally exposed to methamphetamine. [Neurotoxicol Teratol. 2009]
Maternal depression and neurobehavior in newborns prenatally exposed to methamphetamine.
Paz MS, Smith LM, LaGasse LL, Derauf C, Grant P, Shah R, Arria A, Huestis M, Haning W, Strauss A, et al. Neurotoxicol Teratol. 2009 May-Jun; 31(3):177-82. Epub 2008 Dec 3.
Review Vagal activity, early growth and emotional development. [Infant Behav Dev. 2008]
Review Vagal activity, early growth and emotional development.
Field T, Diego M. Infant Behav Dev. 2008 Sep; 31(3):361-73. Epub 2008 Mar 4.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Prenatal anger effects on the fetus and neonate.
Prenatal anger effects on the fetus and neonate.
J Obstet Gynaecol. 2002 May ;22(3):260-6.

PubMed
Postpartum hemorrhage after cesarean delivery: an analysis of risk factors.
Postpartum hemorrhage after cesarean delivery: an analysis of risk factors.
South Med J. 2005 Jul ;98(7):681-5.

PubMed
Impact of diet in shaping gut microbiota revealed by a comparative study in chil...
Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa.
Proc Natl Acad Sci U S A. 2010 Aug 17 ;107(33):14691-6. Epub 2010 Aug 2 .

PubMed
Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methylt...
Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1.
Mol Biol Cell. 2003 Jan ;14(1):274-87.

PubMed
The arginine methyltransferase CARM1 regulates the coupling of transcription and...
The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.
Mol Cell. 2007 Jan 12 ;25(1):71-83.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: