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J Clin Microbiol. 2003 Jan;41(1):453-5.

Identification of Balamuthia mandrillaris by PCR assay using the mitochondrial 16S rRNA gene as a target.

Author information

  • 1Department of Molecular Genetics, The Ohio State University, Columbus, Ohio 43210-1292, USA. booton.1@osu.edu

Abstract

Balamuthia mandrillaris is an opportunistic pathogen that causes granulomatous amebic meningoencephalitis in animals, including humans. Based on sequence analysis of mitochondrial small-subunit-rRNA genes, we developed primers that amplify a Balamuthia-specific PCR product. These primers will be useful for retrospective analyses of fixed tissues and possible identification of Balamuthia in vivo.

PMID:
12517892
[PubMed - indexed for MEDLINE]
PMCID:
PMC149639
Free PMC Article
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