Pitavastatin Nissan/Kowa Yakuhin/Novartis/Sankyo. [Curr Opin Investig Drugs. 2002]

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1: Curr Opin Investig Drugs. 2002 Sep;3(9):1334-41.Links

Pitavastatin Nissan/Kowa Yakuhin/Novartis/Sankyo.

Flores NA.

University College London, Institute of Urology and Nephrology, Division of Applied Physiology, 48 Riding House Street, London, W1W 7EY, UK. naflor40@hotmail.com

Pitavastatin (nisvastatin) is an HMG CoA reductase inhibitor being developed jointly by Nissan, Kowa Kogyo, Novartis and Sankyo for the potential treatment of atherosclerosis and hyperlipidemia.

PMID: 12498010 [PubMed - indexed for MEDLINE]

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[Cardiovasc Drug Rev. 2003]
Review[Pharmacological and pharmacokinetic features and clinical effects of pitavastatin (Livalo Tablet)]
Nippon Yakurigaku Zasshi. 2004 May; 123(5):349-62.

[Nippon Yakurigaku Zasshi. 2004]
Anti-lipid deposition effect of HMG-CoA reductase inhibitor, pitavastatin, in a rat model of hypertension and hypercholesterolemia.
Life Sci. 2004 Mar 12; 74(17):2129-42.

[Life Sci. 2004]
Protective effect of pitavastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, on ischemia-induced neuronal damage.
Neurol Res. 2004 Sep; 26(6):684-91.

[Neurol Res. 2004]
Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMG-CoA reductase.
J Pharm Pharmacol. 2005 Oct; 57(10):1305-11.

[J Pharm Pharmacol. 2005]
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