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Bone Marrow Transplant. 2002 Dec;30(12):983-5.

Human herpesvirus-7 infection of the CNS with acute myelitis in an adult bone marrow recipient.

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  • 1Department of Virology, Royal Free and University College Medical School, Windeyer Institute of Medical Sciences, London, UK.


The beta-herpesviruses, human herpesviruses-6 and -7 (HHV-6 and HHV-7), are closely related and have very similar biological behaviour. While HHV-6 is associated with encephalitis in immunosuppressed adults, HHV-7 is not recognised as a cause of neurological disease in such patients. This report describes the identification of a reactivated HHV-7 infection in the cerebrospinal fluid of an adult who presented with an acute myelitis 11 months after unrelated donor bone marrow transplant.

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