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Ecole Normale Supérieure, CNRS UMR8541, 46 rue d'Ulm, 75230, Paris, France. mdreyfus@biologie.ens.fr
In eukaryotes, poly(A) tails usually act as stabilizers of intact mRNAs, whereas in E. coli they serve to accelerate the destruction of fragments. The mechanisms underlying these contrasting effects of the same RNA modification are discussed.
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