Metabolic control of diabetes in a diabetes centre

Hong Kong Med J. 2002 Dec;8(6):419-26.

Abstract

Objective: To examine the effectiveness of a diabetes centre in restoring metabolic control in patients with poorly controlled diabetes.

Design: Retrospective review of medical records.

Setting: Diabetes centre of a district hospital, Hong Kong.

Participants: Patients with poorly controlled diabetes referred to a diabetes centre.

Main outcome measures: Primary endpoints were mean change in glycated haemoglobin levels and the number of patients who achieved glycated haemoglobin levels of 7.0% or lower, 7.5% or lower, and 8.0% or lower, respectively. Complementary endpoints were serial changes in body weight, blood pressure, and lipids.

Results: One hundred and eighty-five patients, predominantly with type 2 diabetes (94.6%), were reviewed. Median duration since diagnosis of diabetes was 8 years (interquartile range, 4.3-11.8 years). Seventy-three patients had a body mass index of 25 kg/m(2) or higher. The baseline and latest glycated haemoglobin levels were 10.4% (standard deviation, 2%) and 8.2% (1.4%), respectively; mean reduction was 2.2% (95% confidence interval, 1.9-2.5; P<0.0005). Eighty-one patients were discharged after a median 32 weeks of follow-up. Their mean glycated haemoglobin level on discharge was 7.5% (0.8%), and the mean reduction was 2.8% (95% confidence interval, 2.4-3.3; P<0.0005). The cumulative percentages of discharged patients who achieved glycated haemoglobin levels of less than 7.0%, 7.5%, and 8.0% were 30.9%, 53.1%, and 77.8%, respectively. Newly diagnosed diabetes (P=0.006) was the only factor which predicted a favourable glycaemic response. CONCLUSION. The Diabetes Centre provided effective management for a heterogeneous group of patients referred with poorly controlled diabetes.

MeSH terms

  • Adolescent
  • Adult
  • Age of Onset
  • Aged
  • Blood Pressure
  • Body Mass Index
  • Diabetes Mellitus / epidemiology
  • Diabetes Mellitus / metabolism
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / metabolism*
  • Diabetes Mellitus, Type 2 / therapy*
  • Female
  • Glycated Hemoglobin / analysis
  • Hong Kong / epidemiology
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Lipids / analysis
  • Male
  • Medical Records / statistics & numerical data
  • Middle Aged
  • Obesity
  • Outcome and Process Assessment, Health Care / statistics & numerical data
  • Outpatient Clinics, Hospital / statistics & numerical data*
  • Referral and Consultation / statistics & numerical data
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Glycated Hemoglobin A
  • Hypoglycemic Agents
  • Lipids