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Biochimie. 2002 Sep;84(9):841-8.

Developments in RNA chemistry, a personal view.

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  • 1Max-Planck-Institut für experimentelle Medizin, Hermann-Rein-Str. 3, 37075 Göttingen, Germany. eckstein@em.mpg.de

Abstract

This review describes some of the contributions of chemistry to the RNA field with a personal bias towards the phosphorothioate modification and the derivatives at the ribose 2'-position. The usefulness of these modifications is discussed and documented with some examples.

PMID:
12458076
[PubMed - indexed for MEDLINE]

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