Curr Drug Targets Infect Disord. 2001 May;1(1):11-7.

The strategy of immunologic control of HIV-1 with structured treatment interruptions (STIs).

Moss RB, Jensen FC, Carlo DJ, Wallace MR.

Source

Immune Response Corporation, 5935 Darwin Court, Carlsbad, CA 92008, USA.

Abstract

Structured treatment interruptions (STIs) have evolved as an experimental approach of interrupting highly active antiretroviral therapy (HAART) similar to cycles of cancer chemotherapy in order to develop immune control of HIV-1. There are multiple, ongoing clinical trials examining interruptions in antiviral therapy with and without immune-based therapies. If successful in developing immune control, STIs may be clinically useful but require large scale clinical trials to prove their utility and safety.

PMID:: 12455230; [PubMed - indexed for MEDLINE]

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AIDS Vaccines

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