Br J Anaesth. 2002 Dec;89(6):904-16.

Parkinson's disease and anaesthesia.

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Department of Anaesthesia and Intensive Care Medicine, St George's Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK. gnichols@sghms.ac.uk

Abstract

Parkinson's disease is an increasingly common disease of elderly patients who present a particular anaesthetic challenge. This review explores the epidemiology, aetiology, pathogenesis, and pathophysiology of the condition, particularly the possible role of genetic factors. The clinical features are described in detail and recent advances in medical management are highlighted. Controversies surrounding the use of the newer drugs and possible advances in neurosurgical interventions are discussed. Particular anaesthetic problems in patients with Parkinson's disease are respiratory, cardiovascular, and neurological. Potential drug interactions are described and recommendations are made about suitable anaesthetic techniques.

Comment in

Br J Anaesth. 2003 Apr;90(4):524; author reply 524-5.

PMID:: 12453936; [PubMed - indexed for MEDLINE]

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